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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1584731
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smg5
Name: SMG5 nonsense mediated mRNA decay factor
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smg5affects expressionEXP 6480464CTDbisphenol A affects the expression of SMG5 mRNAPMID:25181051
Smg5increases expressionEXP 6480464CTDbisphenol A results in increased expression of SMG5 mRNAPMID:30816183 PMID:34947998
Smg5decreases methylationISOSMG5 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of SMG5 genePMID:31601247
Smg5increases expressionISOSMG5 (Homo sapiens)6480464CTDbisphenol A results in increased expression of SMG5 mRNAPMID:29275510
Smg5multiple interactionsISOSMG5 (Homo sapiens)6480464CTD[[ginger extract results in increased abundance of Oils, Volatile] which co-treated with bisphenol A] affects the expression of SMG5 proteinPMID:33376534
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