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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566130
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fbxo41
Name: F-box protein 41
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxo41decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of FBXO41 mRNA

PMID:25181051, PMID:30816183
Fbxo41increases expressionEXP 6480464CTDbisphenol A results in increased expression of FBXO41 mRNA

PMID:29097150
Fbxo41multiple interactionsISORGD:13512236480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of FBXO41 mRNA

PMID:28628672
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.