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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566064
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prrc2c
Name: proline-rich coiled-coil 2C
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prrc2caffects expressionEXP 6480464CTDbisphenol A affects the expression of PRRC2C mRNAPMID:25181051 PMID:32145629
Prrc2cdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PRRC2C mRNAPMID:34947998
Prrc2cincreases expressionEXP 6480464CTDbisphenol A results in increased expression of PRRC2C mRNAPMID:30816183
Prrc2caffects splicingISOPrrc2c (Mus musculus)6480464CTDbisphenol A affects the splicing of PRRC2C mRNAPMID:37894381
Prrc2cdecreases expressionISOPRRC2C (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PRRC2C proteinPMID:37567409
Prrc2cdecreases expressionISOPrrc2c (Mus musculus)6480464CTDbisphenol A results in decreased expression of PRRC2C mRNAPMID:33221593
Prrc2cincreases expressionISOPRRC2C (Homo sapiens)6480464CTDbisphenol A results in increased expression of PRRC2C proteinPMID:34186270
Prrc2cincreases methylationISOPrrc2c (Mus musculus)6480464CTDbisphenol A results in increased methylation of PRRC2C promoterPMID:27312807
Prrc2cmultiple interactionsISOPRRC2C (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PRRC2C mRNAPMID:28628672
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