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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565043
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arhgef10
Name: Rho guanine nucleotide exchange factor 10
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arhgef10affects expressionEXP 6480464CTDbisphenol A affects the expression of ARHGEF10 mRNAPMID:30816183
Arhgef10decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ARHGEF10 mRNAPMID:25181051
Arhgef10increases expressionEXP 6480464CTDbisphenol A results in increased expression of ARHGEF10 mRNAPMID:32528016
Arhgef10increases methylationISOARHGEF10 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of ARHGEF10 genePMID:31601247
Arhgef10multiple interactionsISOARHGEF10 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of ARHGEF10 genePMID:31601247
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