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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563152
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srgap3
Name: SLIT-ROBO Rho GTPase activating protein 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srgap3increases expressionEXP 6480464CTDbisphenol A results in increased expression of SRGAP3 mRNAPMID:30816183
Srgap3decreases expressionISOSRGAP3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of SRGAP3 mRNAPMID:31715268
Srgap3increases expressionISOSRGAP3 (Homo sapiens)6480464CTDbisphenol A results in increased expression of SRGAP3 mRNAPMID:27685785
Srgap3increases methylationISOSRGAP3 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of SRGAP3 genePMID:31601247
Srgap3increases methylationISOSrgap3 (Mus musculus)6480464CTDbisphenol A results in increased methylation of SRGAP3 promoterPMID:27312807
Srgap3multiple interactionsISOSRGAP3 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of SRGAP3 genePMID:31601247
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