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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561523
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gbp6
Name: guanylate binding protein family member 6
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gbp6increases expressionEXP 6480464CTDbisphenol A results in increased expression of GBP6 mRNAPMID:25181051 PMID:32145629 PMID:35192832
Gbp6multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of GBP6 mRNAPMID:26496021
Gbp6increases expressionISOGbp9 (Mus musculus)6480464CTDbisphenol A results in increased expression of GBP6 mRNAPMID:30951980
Gbp6multiple interactionsISOGBP6 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GBP6 mRNAPMID:28628672
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