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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560819
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chsy3
Name: chondroitin sulfate synthase 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chsy3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CHSY3 mRNAPMID:25181051
Chsy3decreases expressionISOCHSY3 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CHSY3 mRNA; bisphenol A results in decreased expression of CHSY3 proteinPMID:29275510 PMID:33376534
Chsy3decreases methylationISOCHSY3 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of CHSY3 genePMID:31601247
Chsy3increases expressionISOChsy3 (Mus musculus)6480464CTDbisphenol A results in increased expression of CHSY3 mRNAPMID:30951980 PMID:34585602
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