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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557864
Species: Mus musculus
RGD Object: Gene
Symbol: Helq
Name: helicase, POLQ-like
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Helqaffects splicingEXP 6480464CTDbisphenol A affects the splicing of HELQ mRNAPMID:37894381
Helqdecreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of HELQ promoterPMID:27312807
Helqincreases expressionEXP 6480464CTDbisphenol A results in increased expression of HELQ mRNAPMID:33221593
Helqaffects expressionISOHelq (Rattus norvegicus)6480464CTDbisphenol A affects the expression of HELQ mRNAPMID:25181051
Helqincreases expressionISOHelq (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of HELQ mRNAPMID:30816183 PMID:32528016
Helqincreases methylationISOHelq (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of HELQ genePMID:28505145
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