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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557746
Species: Mus musculus
RGD Object: Gene
Symbol: Pde4c
Name: phosphodiesterase 4C, cAMP specific
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde4cdecreases expressionISOPde4c (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of PDE4C mRNAPMID:25181051 PMID:30816183 PMID:32528016
Pde4cdecreases expressionISOPDE4C (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PDE4C mRNAPMID:15223131
Pde4cincreases expressionISOPDE4C (Homo sapiens)6480464CTDbisphenol A results in increased expression of PDE4C mRNAPMID:31715268
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