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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552269
Species: Mus musculus
RGD Object: Gene
Symbol: Sgpl1
Name: sphingosine phosphate lyase 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sgpl1increases expressionEXP 6480464CTDbisphenol A results in increased expression of SGPL1 mRNAPMID:33221593
Sgpl1decreases expressionISOSgpl1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of SGPL1 mRNAPMID:25181051 PMID:32145629
Sgpl1multiple interactionsISOSgpl1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SGPL1 mRNAPMID:36041667
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