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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359545
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prss23
Name: serine protease 23
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prss23decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PRSS23 mRNAPMID:25181051 PMID:34947998
Prss23affects expressionISOPRSS23 (Homo sapiens)6480464CTDbisphenol A affects the expression of PRSS23 mRNAPMID:20170705
Prss23increases expressionISOPRSS23 (Homo sapiens)6480464CTDbisphenol A analog results in increased expression of PRSS23 mRNA; bisphenol A results in increased expression of PRSS23 mRNA; bisphenol A results in increased expression of PRSS23 proteinPMID:22494775 PMID:23384675 PMID:37664457
Prss23increases expressionISOPrss23 (Mus musculus)6480464CTDbisphenol A results in increased expression of PRSS23 mRNAPMID:30951980 PMID:33221593
Prss23multiple interactionsISOPRSS23 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of PRSS23 gene; ESR1 protein affects the reaction [bisphenol A results in increased expression of PRSS23 mRNA]; ESR1 protein inhibits the reaction [bisphenol A analog results in increased expression of PRSS23 mRNA]PMID:23384675 PMID:31601247
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