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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359418
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bhmt2
Name: betaine-homocysteine S-methyltransferase 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bhmt2affects expressionEXP 6480464CTDbisphenol A affects the expression of BHMT2 proteinPMID:32145629
Bhmt2affects methylationEXP 6480464CTDbisphenol A affects the methylation of BHMT2 promoterPMID:27415467
Bhmt2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of BHMT2 mRNAPMID:25181051
Bhmt2increases expressionEXP 6480464CTDbisphenol A results in increased expression of BHMT2 mRNAPMID:34947998
Bhmt2increases expressionISOBHMT2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of BHMT2 mRNAPMID:27685785
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