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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352658
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNH8
Name: potassium voltage-gated channel subfamily H member 8
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNH8affects methylationEXP 6480464CTDbisphenol A affects the methylation of KCNH8 genePMID:31601247
KCNH8affects methylationISOKcnh8 (Mus musculus)6480464CTDbisphenol A affects the methylation of KCNH8 promoterPMID:27334623
KCNH8decreases expressionISOKcnh8 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of KCNH8 mRNAPMID:25181051 PMID:30816183 PMID:32528016
KCNH8increases methylationISOKcnh8 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of KCNH8 genePMID:28505145
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