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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350500
Species: Homo sapiens
RGD Object: Gene
Symbol: TBX18
Name: T-box transcription factor 18
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TBX18affects methylationEXP 6480464CTDbisphenol A affects the methylation of TBX18 genePMID:31601247
TBX18multiple interactionsEXP 6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TBX18 mRNAPMID:28628672
TBX18affects expressionISOTbx18 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of TBX18 mRNAPMID:25181051
TBX18affects methylationISOTbx18 (Mus musculus)6480464CTDbisphenol A affects the methylation of TBX18 promoterPMID:27334623
TBX18decreases expressionISOTbx18 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of TBX18 mRNAPMID:30816183 PMID:34947998
TBX18increases expressionISOTbx18 (Mus musculus)6480464CTDbisphenol A results in increased expression of TBX18 mRNAPMID:30951980
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