GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSPA1A | affects expression | EXP | | 6480464 | CTD | bisphenol A affects the expression of HSPA1A mRNA | PMID:30903817 | HSPA1A | decreases methylation | EXP | | 6480464 | CTD | bisphenol A results in decreased methylation of HSPA1A promoter | PMID:30352284 | HSPA1A | multiple interactions | EXP | | 6480464 | CTD | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HSPA1A mRNA | PMID:28628672 | HSPA1A | affects expression | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | bisphenol A affects the expression of HSPA1A mRNA | PMID:30903817 | HSPA1A | decreases expression | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of HSPA1A mRNA | PMID:26063408 PMID:37611474 | HSPA1A | increases expression | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of HSPA1A mRNA; bisphenol A results in increased expression of HSPA1A protein | PMID:12460799 PMID:33221593 | HSPA1A | increases expression | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of HSPA1A mRNA | PMID:17010207 | HSPA1A | multiple interactions | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | [bisphenol A co-treated with tributyltin] results in decreased expression of HSPA1A mRNA | PMID:31129395 | |
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