GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | EP300 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to EP300 protein modified form]; bisphenol A promotes the reaction [EP300 protein binds to EZH2 promoter]; bisphenol A promotes the reaction [EP300 protein binds to HOTAIR promoter]; bisphenol A promotes the reaction [EP300 protein binds to HOXB9 promoter]; bisphenol A promotes the reaction [EP300 protein binds to HOXC6 promoter]; KMT2D mutant form inhibits the reaction [bisphenol A promotes the reaction [EP300 protein binds to EZH2 promoter]] | PMID:24533973 PMID:25088689 PMID:25725483 PMID:27182052 PMID:28751236 | EP300 | affects methylation | ISO | Ep300 (Mus musculus) | 6480464 | CTD | bisphenol A affects the methylation of EP300 promoter | PMID:27334623 | EP300 | increases expression | ISO | Ep300 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of EP300 mRNA | PMID:25181051 PMID:32145629 PMID:34947998 | |
Go Back to source page | Continue to Ontology report |