GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MMP9 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of MMP9 mRNA; bisphenol A results in decreased expression of MMP9 protein | PMID:31230753 PMID:32981897 | MMP9 | decreases methylation | EXP | | 6480464 | CTD | bisphenol A results in decreased methylation of MMP9 gene | PMID:31601247 | MMP9 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of MMP9 mRNA; bisphenol A results in increased expression of MMP9 protein | PMID:19956873 PMID:24997338 PMID:25312822 PMID:25534675 PMID:25690688 PMID:26604029 PMID:27038254 PMID:28844962 PMID:33437163 PMID:33469997 PMID:33683587 | MMP9 | increases secretion | EXP | | 6480464 | CTD | bisphenol A results in increased secretion of MMP9 protein | PMID:18585891 | MMP9 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; 3,3'-diindolylmethane inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased secretion of MMP9 protein; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; Asian ginseng inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; Asian ginseng inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; bisphenol A promotes the reaction [BRAF protein mutant form results in increased expression of MMP9 protein]; bisphenol A results in increased expression of and results in increased activity of MMP9 protein; ESRRG protein affects the reaction [bisphenol A results in increased expression of MMP9 mRNA]; ESRRG protein affects the reaction [bisphenol A results in increased expression of MMP9 protein]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; RTKI cpd inhibits the reaction [bisphenol A results in increased expression of MMP9 protein] | PMID:19956873 PMID:24997338 PMID:25312822 PMID:25534675 PMID:25690688 PMID:27038254 PMID:28844962 PMID:30398665 PMID:33437163 PMID:33469997 | MMP9 | affects expression | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | bisphenol A affects the expression of MMP9 mRNA | PMID:25181051 | MMP9 | affects expression | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | bisphenol A affects the expression of MMP9 mRNA | PMID:35341816 | MMP9 | decreases expression | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of MMP9 mRNA | PMID:32145629 PMID:34884472 | MMP9 | decreases expression | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of MMP9 mRNA | PMID:30303745 PMID:30675821 PMID:34585602 | MMP9 | increases expression | ISO | Mmp9 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of MMP9 mRNA | PMID:27925325 PMID:29323181 PMID:30816183 | MMP9 | increases expression | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of MMP9 mRNA; bisphenol A results in increased expression of MMP9 protein | PMID:32156529 PMID:35752395 | MMP9 | multiple interactions | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | [bisphenol A affects the susceptibility to [Lipopolysaccharides co-treated with IFNG protein]] which results in decreased expression of MMP9 mRNA; bisphenol A inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MMP9 mRNA]; bisphenol A results in increased expression of and results in increased secretion of and results in increased activity of MMP9 protein; Decitabine inhibits the reaction [[bisphenol A affects the susceptibility to [Lipopolysaccharides co-treated with IFNG protein]] which results in decreased expression of MMP9 mRNA] | PMID:28903498 PMID:29718165 | | ||||||||||||||||||||||
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