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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347570
Species: Homo sapiens
RGD Object: Gene
Symbol: AP1AR
Name: adaptor related protein complex 1 associated regulatory protein
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AP1ARaffects expressionEXP 6480464CTDbisphenol A affects the expression of AP1AR mRNAPMID:30903817
AP1ARdecreases expressionISOAp1ar (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of AP1AR mRNAPMID:25181051
AP1ARdecreases expressionISOAp1ar (Mus musculus)6480464CTDbisphenol A results in decreased expression of AP1AR mRNAPMID:33221593
AP1ARmultiple interactionsISOAp1ar (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Genistein] results in increased methylation of AP1AR genePMID:28505145
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