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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346613
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP27A1
Name: cytochrome P450 family 27 subfamily A member 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP27A1increases expressionEXP 6480464CTDbisphenol A results in increased expression of CYP27A1 mRNAPMID:27685785 PMID:29275510
CYP27A1affects expressionISOCyp27a1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of CYP27A1 mRNAPMID:30903817
CYP27A1decreases expressionISOCyp27a1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of CYP27A1 mRNAPMID:32145629
CYP27A1increases expressionISOCyp27a1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of CYP27A1 mRNAPMID:25181051
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