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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345861
Species: Homo sapiens
RGD Object: Gene
Symbol: DUSP3
Name: dual specificity phosphatase 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DUSP3increases expressionEXP 6480464CTDbisphenol A results in increased expression of DUSP3 proteinPMID:37567409
DUSP3affects expressionISODusp3 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of DUSP3 mRNAPMID:25181051
DUSP3decreases expressionISODusp3 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of DUSP3 mRNAPMID:30816183 PMID:32528016 PMID:34947998
DUSP3increases expressionISODusp3 (Mus musculus)6480464CTDbisphenol A results in increased expression of DUSP3 mRNAPMID:26063408
DUSP3increases methylationISODusp3 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of DUSP3 genePMID:28505145
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