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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345091
Species: Homo sapiens
RGD Object: Gene
Symbol: CEP170B
Name: centrosomal protein 170B
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CEP170Bmultiple interactionsEXP 6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of CEP170B mRNAPMID:28628672
CEP170Bdecreases expressionISOCep170b (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of CEP170B mRNAPMID:25181051 PMID:32145629
CEP170Bdecreases methylationISOCep170b (Mus musculus)6480464CTDbisphenol A results in decreased methylation of CEP170B promoterPMID:27312807
CEP170Bincreases expressionISOCep170b (Mus musculus)6480464CTDbisphenol A results in increased expression of CEP170B mRNAPMID:32156529
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