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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344896
Species: Homo sapiens
RGD Object: Gene
Symbol: HOXA3
Name: homeobox A3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HOXA3increases expressionEXP 6480464CTDbisphenol A results in increased expression of HOXA3 mRNAPMID:27685785
HOXA3increases methylationEXP 6480464CTDbisphenol A results in increased methylation of HOXA3 genePMID:31601247
HOXA3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of HOXA3 genePMID:31601247
HOXA3affects expressionISOHoxa3 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of HOXA3 mRNAPMID:25181051
HOXA3affects methylationISOHoxa3 (Mus musculus)6480464CTDbisphenol A affects the methylation of HOXA3 promoterPMID:27334623
HOXA3increases expressionISOHoxa3 (Mus musculus)6480464CTDbisphenol A results in increased expression of HOXA3 mRNAPMID:30951980
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