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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344629
Species: Homo sapiens
RGD Object: Gene
Symbol: ATP8A2
Name: ATPase phospholipid transporting 8A2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATP8A2affects methylationEXP 6480464CTDbisphenol A affects the methylation of ATP8A2 genePMID:31601247
ATP8A2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of ATP8A2 genePMID:31601247
ATP8A2decreases expressionISOAtp8a2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ATP8A2 mRNAPMID:25181051 PMID:30816183 PMID:32528016
ATP8A2increases expressionISOAtp8a2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ATP8A2 mRNAPMID:29097150
ATP8A2increases expressionISOAtp8a2 (Mus musculus)6480464CTDbisphenol A results in increased expression of ATP8A2 mRNAPMID:34585602
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