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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1342700
Species: Homo sapiens
RGD Object: Gene
Symbol: KIF4A
Name: kinesin family member 4A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KIF4Adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of KIF4A mRNAPMID:29275510
KIF4Aincreases expressionEXP 6480464CTDbisphenol A results in increased expression of KIF4A mRNAPMID:16474171
KIF4Aincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of KIF4A genePMID:31601247
KIF4Amultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of KIF4A gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of KIF4A mRNAPMID:28628672 PMID:31601247
KIF4Adecreases expressionISOKif4 (Mus musculus)6480464CTDbisphenol A results in decreased expression of KIF4 mRNAPMID:26063408
KIF4Adecreases expressionISOKif4a (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of KIF4A mRNAPMID:25181051
KIF4Aincreases expressionISOKif4a (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of KIF4A mRNAPMID:32145629
KIF4Amultiple interactionsISOKif4a (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of KIF4A mRNAPMID:26496021
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