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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332500
Species: Mus musculus
RGD Object: Gene
Symbol: Myod1
Name: myogenic differentiation 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myod1affects methylationEXP 6480464CTDbisphenol A affects the methylation of MYOD1 promoterPMID:27334623
Myod1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of MYOD1 proteinPMID:29680376
Myod1decreases expressionISOMyod1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of MYOD1 mRNAPMID:25181051 PMID:27178563
Myod1increases methylationISOMyod1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of MYOD1 genePMID:28505145
Myod1multiple interactionsISOMYOD1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Quercetin metabolite] results in increased expression of MYOD1 mRNA; [bisphenol A co-treated with Quercetin] results in increased expression of MYOD1 mRNA; [naringenin co-treated with bisphenol A] results in increased expression of MYOD1 mRNA; [naringenin metabolite co-treated with bisphenol A] results in increased expression of MYOD1 mRNAPMID:36235125 PMID:36982678
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