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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332035
Species: Mus musculus
RGD Object: Gene
Symbol: Crtc2
Name: CREB regulated transcription coactivator 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Crtc2increases expressionISOCrtc2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of CRTC2 mRNAPMID:25181051 PMID:30816183 PMID:34947998 PMID:36137816
Crtc2increases methylationISOCrtc2 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of CRTC2 genePMID:28505145
Crtc2increases phosphorylationISOCrtc2 (Rattus norvegicus)6480464CTDbisphenol A results in increased phosphorylation of CRTC2 proteinPMID:36137816
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