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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321777
Species: Homo sapiens
RGD Object: Gene
Symbol: ACAP3
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACAP3increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ACAP3 genePMID:31601247
ACAP3affects expressionISOAcap3 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of ACAP3 mRNAPMID:25181051
ACAP3increases expressionISOAcap3 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ACAP3 mRNAPMID:34947998
ACAP3multiple interactionsISOAcap3 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of ACAP3 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of ACAP3 promoterPMID:23359474 PMID:36041667
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