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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321664
Species: Mus musculus
RGD Object: Gene
Symbol: Fndc1
Name: fibronectin type III domain containing 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fndc1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of FNDC1 mRNAPMID:38074096
Fndc1increases expressionEXP 6480464CTDbisphenol A results in increased expression of FNDC1 mRNAPMID:30245210 PMID:30951980 PMID:32156529 PMID:32370801
Fndc1decreases expressionISOFndc1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of FNDC1 mRNAPMID:25181051 PMID:34947998
Fndc1decreases methylationISOFNDC1 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of FNDC1 genePMID:31601247
Fndc1multiple interactionsISOFNDC1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of FNDC1 genePMID:31601247
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