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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321590
Species: Mus musculus
RGD Object: Gene
Symbol: Ints8
Name: integrator complex subunit 8
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ints8decreases expressionISOINTS8 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of INTS8 proteinPMID:33376534
Ints8increases expressionISOInts8 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of INTS8 mRNAPMID:25181051
Ints8multiple interactionsISOINTS8 (Homo sapiens)6480464CTD[ginger extract results in increased abundance of Oils, Volatile] inhibits the reaction [bisphenol A results in decreased expression of INTS8 protein]PMID:33376534
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