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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321579
Species: Homo sapiens
RGD Object: Gene
Symbol: ELF2
Name: E74 like ETS transcription factor 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ELF2decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of ELF2 genePMID:31601247
ELF2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of ELF2 genePMID:31601247
ELF2affects methylationISOElf2 (Mus musculus)6480464CTDbisphenol A affects the methylation of ELF2 promoterPMID:27334623
ELF2decreases expressionISOElf2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ELF2 mRNAPMID:25181051
ELF2increases expressionISOElf2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ELF2 mRNAPMID:34947998
ELF2increases expressionISOElf2 (Mus musculus)6480464CTDbisphenol A results in increased expression of ELF2 mRNAPMID:33221593
ELF2increases methylationISOElf2 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of ELF2 genePMID:28505145
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