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RGD ID: 1320169
Species: Mus musculus
RGD Object: Gene
Symbol: Pprc1
Name: peroxisome proliferative activated receptor, gamma, coactivator-related 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13096886480464CTDbisphenol A results in increased expression of PPRC1 mRNA

PMID:25181051, PMID:30816183
multiple interactionsISORGD:13201686480464CTD[bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to PPRC1 protein modified form], bisphenol A inhibits the reaction [ESR1 protein binds to PPRC1 protein]

PMID:28751236, PMID:29389661
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.