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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320021
Species: Homo sapiens
RGD Object: Gene
Symbol: ANKFY1
Name: ankyrin repeat and FYVE domain containing 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ANKFY1increases expressionEXP 6480464CTDbisphenol A results in increased expression of ANKFY1 mRNAPMID:29275510
ANKFY1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ANKFY1 genePMID:31601247
ANKFY1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of ANKFY1 gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ANKFY1 mRNAPMID:28628672 PMID:31601247
ANKFY1affects expressionISOAnkfy1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of ANKFY1 mRNAPMID:32145629
ANKFY1decreases expressionISOAnkfy1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ANKFY1 mRNAPMID:26982218
ANKFY1increases expressionISOAnkfy1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ANKFY1 mRNAPMID:30816183
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