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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319221
Species: Mus musculus
RGD Object: Gene
Symbol: Gadd45b
Name: growth arrest and DNA-damage-inducible 45 beta
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gadd45bdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GADD45B mRNAPMID:25385582
Gadd45bincreases expressionEXP 6480464CTDbisphenol A results in increased expression of GADD45B mRNAPMID:32156529
Gadd45bdecreases expressionISOGadd45b (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of GADD45B mRNAPMID:30816183 PMID:32145629 PMID:32528016
Gadd45bdecreases expressionISOGADD45B (Homo sapiens)6480464CTDbisphenol A results in decreased expression of GADD45B mRNAPMID:25047013 PMID:27685785
Gadd45bincreases expressionISOGadd45b (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of GADD45B mRNAPMID:25181051 PMID:27143994
Gadd45bmultiple interactionsISOGadd45b (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of GADD45B mRNAPMID:36041667
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