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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318351
Species: Homo sapiens
RGD Object: Gene
Symbol: EFEMP1
Name: EGF containing fibulin extracellular matrix protein 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EFEMP1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of EFEMP1 genePMID:31601247
EFEMP1decreases expressionISOEfemp1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of EFEMP1 mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
EFEMP1increases expressionISOEfemp1 (Mus musculus)6480464CTDbisphenol A results in increased expression of EFEMP1 mRNAPMID:30951980
EFEMP1increases methylationISOEfemp1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of EFEMP1 genePMID:28505145
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