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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317702
Species: Homo sapiens
RGD Object: Gene
Symbol: AATK
Name: apoptosis associated tyrosine kinase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AATKdecreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of AATK genePMID:31601247
AATKmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of AATK genePMID:31601247
AATKaffects expressionISOAatk (Rattus norvegicus)6480464CTDbisphenol A affects the expression of AATK mRNAPMID:25181051
AATKdecreases expressionISOAatk (Mus musculus)6480464CTDbisphenol A results in decreased expression of AATK mRNAPMID:32156529
AATKdecreases methylationISOAatk (Mus musculus)6480464CTDbisphenol A results in decreased methylation of AATK promoterPMID:27312807
AATKincreases expressionISOAatk (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of AATK mRNAPMID:30816183 PMID:34947998
AATKmultiple interactionsISOAatk (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of AATK mRNAPMID:36041667
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