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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317623
Species: Homo sapiens
RGD Object: Gene
Symbol: CCM2
Name: CCM2 scaffold protein
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCM2decreases expressionISOCcm2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of CCM2 mRNAPMID:25181051
CCM2increases expressionISOCcm2 (Mus musculus)6480464CTDbisphenol A results in increased expression of CCM2 mRNAPMID:32156529
CCM2increases methylationISOCcm2 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of CCM2 genePMID:28505145
CCM2multiple interactionsISOCcm2 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CCM2 mRNAPMID:36041667
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