Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316657
Species: Homo sapiens
RGD Object: Gene
Symbol: TIAM1
Name: TIAM Rac1 associated GEF 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TIAM1affects methylationEXP 6480464CTDbisphenol A affects the methylation of TIAM1 genePMID:31601247
TIAM1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of TIAM1 genePMID:22576693
TIAM1increases expressionEXP 6480464CTDbisphenol A results in increased expression of TIAM1 mRNAPMID:22576693
TIAM1affects expressionISOTiam1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of TIAM1 mRNAPMID:25181051
TIAM1decreases expressionISOTiam1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of TIAM1 mRNAPMID:30816183 PMID:34947998
TIAM1multiple interactionsISOTiam1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of TIAM1 mRNAPMID:26496021
Go Back to source page   Continue to Ontology report