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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314307
Species: Mus musculus
RGD Object: Gene
Symbol: Nck2
Name: non-catalytic region of tyrosine kinase adaptor protein 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nck2increases expressionEXP 6480464CTDbisphenol A results in increased expression of NCK2 mRNAPMID:32156529
Nck2affects expressionISONck2 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of NCK2 mRNAPMID:25181051
Nck2affects methylationISONCK2 (Homo sapiens)6480464CTDbisphenol A affects the methylation of NCK2 genePMID:31601247
Nck2increases expressionISONck2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of NCK2 mRNAPMID:30816183 PMID:34947998
Nck2multiple interactionsISONCK2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of NCK2 genePMID:31601247
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