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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311158
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Brf1
Name: BRF1, RNA polymerase III transcription initiation factor subunit
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Brf1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of BRF1 mRNAPMID:33296240
Brf1increases expressionEXP 6480464CTDbisphenol A results in increased expression of BRF1 mRNAPMID:25181051
Brf1decreases expressionISOBrf1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of BRF1 mRNAPMID:37894381
Brf1decreases methylationISOBRF1 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of BRF1 genePMID:31601247
Brf1increases expressionISOBRF1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of BRF1 proteinPMID:32981897
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