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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310849
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ipo7
Name: importin 7
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ipo7decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of IPO7 mRNA; bisphenol A results in decreased expression of IPO7 proteinPMID:30816183 PMID:32145629 PMID:34947998
Ipo7increases expressionEXP 6480464CTDbisphenol A results in increased expression of IPO7 mRNAPMID:25181051
Ipo7increases methylationEXP 6480464CTDbisphenol A results in increased methylation of IPO7 genePMID:28505145
Ipo7multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of IPO7 mRNAPMID:26496021
Ipo7affects expressionISOIpo7 (Mus musculus)6480464CTDbisphenol A affects the expression of IPO7 mRNAPMID:26063408
Ipo7multiple interactionsISOIPO7 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of IPO7 gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of IPO7 mRNAPMID:28628672 PMID:31601247
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