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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310783
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cnot6
Name: CCR4-NOT transcription complex, subunit 6
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CNOT6 mRNA

PMID:25181051
increases methylationEXP 6480464CTDbisphenol A results in increased methylation of CNOT6 gene

PMID:28505145
multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of CNOT6 mRNA

PMID:26496021
decreases expressionISORGD:15517826480464CTDbisphenol A results in decreased expression of CNOT6 mRNA

PMID:25270620
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