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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310590
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eps8
Name: EGFR pathway substrate 8, signaling adaptor
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eps8decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of EPS8 mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
Eps8affects localizationISOEPS8 (Homo sapiens)6480464CTDbisphenol A affects the localization of EPS8 proteinPMID:24532171
Eps8decreases expressionISOEps8 (Mus musculus)6480464CTDbisphenol A results in decreased expression of EPS8 mRNAPMID:26063408
Eps8increases expressionISOEps8 (Mus musculus)6480464CTDbisphenol A results in increased expression of EPS8 mRNAPMID:35479511
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