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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307761
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmgn1
Name: high mobility group nucleosome binding domain 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgn1increases expressionEXP 6480464CTDbisphenol A results in increased expression of HMGN1 mRNAPMID:25181051 PMID:26982218 PMID:34947998
Hmgn1decreases expressionISOHMGN1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of HMGN1 proteinPMID:33376534
Hmgn1increases expressionISOHMGN1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of HMGN1 proteinPMID:34186270
Hmgn1multiple interactionsISOHMGN1 (Homo sapiens)6480464CTD[[ginger extract results in increased abundance of Oils, Volatile] which co-treated with bisphenol A] affects the expression of HMGN1 proteinPMID:33376534
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