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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306851
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gtf2e1
Name: general transcription factor IIE subunit 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gtf2e1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GTF2E1 mRNAPMID:30816183 PMID:32528016
Gtf2e1increases expressionEXP 6480464CTDbisphenol A results in increased expression of GTF2E1 mRNAPMID:25181051 PMID:34947998
Gtf2e1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of GTF2E1 mRNAPMID:26496021
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