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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304859
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sh3glb1
Name: SH3 domain -containing GRB2-like endophilin B1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sh3glb1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SH3GLB1 mRNA; bisphenol A results in decreased expression of SH3GLB1 proteinPMID:32145629 PMID:34947998
Sh3glb1increases expressionEXP 6480464CTDbisphenol A results in increased expression of SH3GLB1 mRNAPMID:25181051 PMID:30816183
Sh3glb1decreases expressionISOSH3GLB1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of SH3GLB1 proteinPMID:31675489
Sh3glb1decreases methylationISOSh3glb1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of SH3GLB1 promoterPMID:27312807
Sh3glb1increases expressionISOSH3GLB1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of SH3GLB1 proteinPMID:34186270
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