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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304755
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Phlda2
Name: pleckstrin homology-like domain, family A, member 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Phlda2affects expressionEXP 6480464CTDbisphenol A affects the expression of PHLDA2 mRNAPMID:25181051
Phlda2affects expressionISOPHLDA2 (Homo sapiens)6480464CTDbisphenol A affects the expression of PHLDA2 mRNAPMID:30903817
Phlda2decreases expressionISOPhlda2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of PHLDA2 mRNAPMID:26063408
Phlda2multiple interactionsISOPHLDA2 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PHLDA2 mRNAPMID:28628672
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