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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304738
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ube4b
Name: ubiquitination factor E4B
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ube4baffects expressionEXP 6480464CTDbisphenol A affects the expression of UBE4B mRNA

PMID:25181051
Ube4bincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of UBE4B gene

PMID:28505145
Ube4bincreases expressionISORGD:13123556480464CTDbisphenol A results in increased expression of UBE4B mRNA

PMID:29275510
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.