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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303149
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Krt85
Name: keratin 85
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Krt85decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of KRT85 mRNAPMID:25181051
Krt85increases methylationEXP 6480464CTDbisphenol A results in increased methylation of KRT85 genePMID:28505145
Krt85decreases expressionISOKRT85 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of KRT85 proteinPMID:33376534
Krt85decreases methylationISOKrt85 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of KRT85 promoterPMID:27312807
Krt85increases methylationISOKrt85 (Mus musculus)6480464CTDbisphenol A results in increased methylation of KRT85 promoterPMID:27312807
Krt85multiple interactionsISOKRT85 (Homo sapiens)6480464CTDbisphenol A promotes the reaction [KRT85 protein binds to ESR1 protein]PMID:27156127
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