GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Npc1l1 | decreases expression | ISO | Npc1l1 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of NPC1L1 mRNA | PMID:32156529 | Npc1l1 | increases expression | ISO | NPC1L1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of NPC1L1 mRNA; bisphenol A results in increased expression of NPC1L1 protein | PMID:28057006 | Npc1l1 | increases expression | ISO | Npc1l1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of NPC1L1 mRNA; bisphenol A results in increased expression of NPC1L1 protein | PMID:34585602 PMID:37701206 | Npc1l1 | multiple interactions | ISO | NPC1L1 (Homo sapiens) | 6480464 | CTD | SREBF2 promotes the reaction [bisphenol A results in increased expression of NPC1L1 mRNA] | PMID:28057006 | Npc1l1 | multiple interactions | ISO | Npc1l1 (Mus musculus) | 6480464 | CTD | [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of NPC1L1 mRNA; Curcumin inhibits the reaction [bisphenol A results in increased expression of NPC1L1 protein] | PMID:30722647 PMID:37701206 | |
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