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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11129
Species: Mus musculus
RGD Object: Gene
Symbol: Pou1f1
Name: POU domain, class 1, transcription factor 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pou1f1affects methylationEXP 6480464CTDbisphenol A affects the methylation of POU1F1 promoterPMID:27334623
Pou1f1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of POU1F1 mRNAPMID:29092056
Pou1f1decreases expressionISOPou1f1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of POU1F1 mRNA; bisphenol A results in decreased expression of POU1F1 mRNA alternative formPMID:16323634 PMID:25181051
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